NFL Week 6 Picks Against The Spread 2016: Predictions, Updated Las Vegas Odds For Every Game ATS

Underdogs continue to get the better of favorites in the 2016 NFL season, going 9-5 against the spread in Week 5. In order for the trend to change in Week 6, the favorites will have to cover some large betting lines. Five teams are favored by at least a touchdown, according to the latest point spreads. Four teams are underdogs at home, including one team with a winning record.